Sildenafil is a generic medical compound which was synthesised by an elite group of scientists associated with the pharmaceutical giant—Pfizer in the mid-1990’s. The formulation of Sildenafil Citrate 100mg tablets was done with the vision to treat hypertension and angina. But, during the initial studies, the medicine was found to have a very mild effect on angina. Such failure in the experiments caused a big disappointment to the scientists but the team persevered with subsequent trials. Soon it was found in a trial that Sildenafil was affecting the erectile dysfunction in men much more positively than other physical ailments. Such discovery led the company to patent the drug in 1996, and about a couple of years later in 1998, Sildenafil Citrate was approved by FDA for the treatment of erectile dysfunction.
Sildenafil became the first oral treatment which was approved by the government authorities for the treatment of erectile dysfunction. Soon, the generic sildenafil pills were marketed by the company for the sale and as per the records, the sales figures of this particular pharmaceutical drug touched almost US$ 2 billion mark.
How Does Sildenafil Citrate Work On Erectile Dysfunction?
Tablets of Sildenafil Citrate 100mg, when kicks in the system reduce the excess calcium deposit around the smooth muscles of the penis. The medical compound enables the brain to release more dopamine when the user gets some sexual stimulation. Also, on dissolving fully into the bloodstream, the chemical agents present in the drug target the blood vessels of the entire body, especially the penile region and opens up the blocked regions of the vessels to promote the flow of oxygenated blood to the organ. On receiving the sufficient amount of blood in the reproductive system, along with the release of the optimum level of dopamine, the user feels revitalised in the reproductive organ and able to achieve a healthy and desired erection. The whole chemical process takes about 20 – 30 minutes to work in the human body.
The optimum Dose Of Sildenafil To Achieve A Perfect Erection
A human body usually can’t withstand the sudden chemical change in the body. That’s why doctors recommended an ED-affected patient to start off with a mild dose of Sildenafil Citrate 100mg . It allows the body to cope up with the changing balance of the endogenous chemicals and react positively over the period of time. ED patients are recommended to gradually increase the dose of Sildenafil Citrate 100 mg, with doctor’s consultation. This increment in the quantity of the medical compound ensures a continuous improvement in the quality of the erection.
Though there are other ED medications available which claim to contain sildenafil citrate as the prime ingredient, the aforementioned medicines are known to be the best in the class and are the cheapest ED drugs.